The section is focused on the use of new biotechnological methods and tools in human medicine or other important areas of human health and disease. These new methods and tools can be used for diagnosis and treatment of diverse pathophysiological conditions (including cancer). They include classical monoclonal antibodies and second generation antibodies useful of targeting the diseased cells and an original novel approach to tumor therapy through mitochondria as a target of anti-tumor therapy.
Hybridoma technology, synthetic antibodies, antibody-drug conjugates, protein engineering of antibodies, interferon-gamma, diagnosis and treatment of cancer
Kateřina Rohlenová, Institute of Biotechnology, ASCR, Czech Republic: Electron transport chain disruption as a new strategy to suppress Her2high breast cancer
Irena Adkins, Sotio, Czech Republic: Immunogenic cell death in lung cancer immunotherapy
Jana Pěknicová, Institute of Biotechnology, ASCR, Czech Republic: Evaluating the quality of male sperm cells with monoclonal antibodies
Pavla Postlerova, Institute of Biotechnology, ASCR, Czech Republic: Monoclonal and polyclonal antibodies as tools for the study of proteins in the male reproductive tract
Tomáš Koval, Institute of Biotechnology, ASCR, Czech Republic: Zinc-dependent 3'nucleases related to treatment of human diseases
Zora Nováková, Institute of Biotechnology, ASCR, Czech Republic: Development of novel biologics for prostate cancer imaging
Petr Malý, Institute of Biotechnology, ASCR, Czech Republic: Glycopeptide mimetics derived from albumin-binding domain scaffold as tools for induction of neutralizing antibodies against HIV-1 gp120 glycoprotein
The section is focused on biotechnological tools for pharmaceutical applications. The aim is to cover the advances in drug discovery and development based on the use of microbial biotechnology. Contributions on screening of biological activities of natural compounds and/or production of secondary or specialized metabolites (antibiotics, immunosuppressors, antitumors etc.) and bioactive peptides and proteins (enzymes, vaccines) by homologous and heterologous microbial hosts are especially welcome. Advances in fermentation technology and strain improvement of classical or novel microbial production processes are acceptable if addressed to pharmaceutical applications, with a particular attention to the recombinant technologies and the integration of chemical and biological aspects in upstream and downstream processes. Co-cultivation approach and metagenomics tools to drug discovery are considered extremely appealing for the state of the art of this section.
Secondary (specialized) metabolites, natural products, fermentation processes, recombinant proteins, pharmaceutical bioprocess design, co-cultivation, metagenomics
Vera Luginbühl, Institute of Chemistry and Biotechnology, ZHAW, Switzerland: 5-Aminolevulinic acid in glioblastoma surgery and intracellular tumour targeting by a shiga toxin subunit B
Flavia Marinelli, Department of Biotechnology, University of Insubria, Italy: Old and novel glycopeptide antibiotics: from product to gene and back
Yi He, College of Food Science and Engineering, Wuhan Polytechnic University, China: Uncovering citrinin biosynthesis in Monascus ruber by reconstructing its biosynthetic pathway in the secondary host Aspergillus oryzae
This session spans all aspects of microalgae biotechnology. Of particular interest are products from microalgae; microalgae for human and animal consumption, microalgae in novel foods and food supplements, microalgae as a source of fine chemicals; photobioreactors and other technologies for large-scale production of microalgal biomass; the methods of harvesting microalgae; downstream processing of algal biomass for product recovery; and the use of algae in environmental applications. Contributions on potential algal biofuels and biorefineries based on microalgae are particularly welcome.
Microalgae; bioproducts; biofuels; biorefineries; production of algal biomass; downstream processing; environmental applications of microalgae
Kateřina Bišová, Institute of Microbiology, ASCR, Czech Republic: Microalgae grown in stable isotopes
Tomas Branyik, Department of Biotechnology, UCT Prague, Czech Republic: Influence of inorganic salt precipitates on autoflocculation of microalgae
Cristina Gonzalez, IMDEA Energy Institute, Spain: Identifying knowledge gaps for an efficient anaerobic digestion of microalgae biomass
Shigeyuki Kawano, University of Tokyo, Japan: Endopolyploidy, fragmentation and reconstitution of chromosomes by the heavy-ion beam irradiation in Parachlorella kessleri
The section is focused on the study and use of biological systems for remediation of contaminated environments - land, air and water. The aim is to show recent development and achievements in the use of biotechnological tools such as engineered microbial consortia or task-specific application of strains and enzymes for environmental protection. Special attention will be paid to material and energy recovery from waste and wastewater in accordance with principles of circular economy.
Anaerobic digestion, biorefineries, circular economy, environmental protection, waste valorisation.
The Food and Agriculture Biotechnology session will focus on sustainable food production (raw materials, processing, packaging, storage); food quality/safety and food adulteration. Presentations are welcome on the detection and control of spoilage and pathogenic microorganisms; development and applications of novel enzymes; functional foods with new and improved properties; nutritional supplements with value added output traits; development of food and agricultural products with new properties by genetic engineering. A particular area of interest is application of biotechnology in agriculture.
food production, quality, safety, adulteration, control of pathogenic microorganisms, novel enzymes, functional foods, nutritional supplements, genetic engineering, biotechnology in agriculture
The section is focused on searching new ways how to process different kinds of waste and to obtain valuable compounds such as biofuels, bioplastics building blocks and others with the help of microorganisms. Contributions describing emerging processes combining physico-chemical waste pre-treatment with biological process like syngas production followed with gas fermentation or biomass fractionalization with microbial production/catalysis are especially welcome. Also advances and/or blindspots of “established“ utilization of second generation feedstocks including synthetic biology approaches for improvement of microbial skills, application of new generation enzymes for release of fermentable compounds from the complex material and original ideas how to overcome current bottlenecks are equally welcome.
waste processing, biofuels, bioplastics, green chemicals, biomass fractionalization, bioprocess design
This session focuses on the identification and control of key process parameters which affect cell growth, metabolism, productivity or product quality, as a satisfactory level of process understanding is considered as key to an industrial process design. Contributions related to technologies and methods utilizing bacteria, yeast, algae or mammalian cells as host organisms and focusing on the identification of key process parameters such as high throughput screening and related statistical (multivariate) data analysis are very welcome. Relevant to this session are also contributions which discuss the development of upstream process models in support of a most optimal process control strategy and/or optimization of processes, covering both fed-batch as well continuous operation. This session also covers synthetic biology approaches paving the way for the development of processes for products which up to now could not be economically synthesized in large amounts neither by making use of chemical nor biological technologies.
process parameters identification, high throughput screening, mathematical modeling and statistical data analysis, optimal process control strategy, cell metabolism and media optimization, synthetic biology
All registered participants can submit a poster for the conference. As long as criteria of scientific and formal quality are met, contributions to the poster session are open to any biotechnology research topic beyond the main scope of the lectures.